Research Centers & Facilities
- Nano Drug Delivery Facility
- Cell Culture Facility
- Cell Imaging Facility
- Protein Biochemistry and Autoradiography Facility
- Microbiology Lab Facility
CENTERA - Center for Nanotechnology Education, Research and Applications
The Center for Nanotechnology Education, Research and Applications is focused on research within the community to expand knowledge of nanotechnology.
Please visit CENTERAâ€™s webpage for more details
Nano Drug Delivery Facility
This lab is well-equipped for developing nano dispersions for drugs, as well as nutraceutical ingredients. We have successful developed several nano emulsion formulations for Donepezil HCl, Physostigmine HCl and Antioxidant Nutraceuticals.
We are collaborating with many laboratories in the University of Louisville for characterization of Nanoparticulate Drug Delivery Systems (NPDDS). Some of the facilities available through our collaborators are: scanning electron microscope (SEM), transmission electron microscope (TEM), Raman Spectrometer, Chemical Vapor Deposition System, and Pulse Vapor Deposition System.
Cell Culture Facility
SUCOP Cell Culture Facility is equipped with state-of-the-art equipments and supplies to conduct research in many different disciplines. This cell culture facility serves as an in-vitro model to test the efficacy of many things including drug formulations, hormones, environmental pollutants, xenobiotics, transgenes, and nanovectors.
This facility is instrumental in many areas of research including:
- Cardiovascular Research
- Cancer Research
- Pharmacology/Toxicology Research
- Research in Endocrinology
- Research in Neurobiology
- Cell Biology & Protein Biochemistry Research
- Research in Therapeutics
- Nanotechnology Research
- Nano Pharmaceutics
Cell Imaging Facility
Cell imaging facility of SUCOP has been established by Drs. Kothwal and Sumanasekera. Currently this facility allows observation and capturing of cell images. Both phase contrast and bright field images of cells can be obtained. The state of the art quality Nikon microscope consists of inverted light source, three objectives (4X, 10X, and 20X), a camera, and a cell imaging software.
SUCOP plans to expand this facility to capture florescence cell images in near future.
The above phase contrast image of rat cardiac stem cells subjected to an apoptosis assay based on immune histochemistry was taken using this facility.
Protein Biochemistry and Autoradiography Facility
Protein Biochemistry and Autoradiography Facility of Sullivan University College of Pharmacy consists of complete SDS Polyacrylamide protein gel electrophoresis system (apparatus for gel assembly, running, transfer), A dark room, and an autoradiogram developer (mini X-ray film processor). This facility allows investigators to conduct protein Biochemistry experiments such as protein gel electrophoresis followed by western blotting, detection and quantification of proteins. Recently Dr. Sumanasekera has established this facility and using this facility currently she is investigating "The effects of cigarette smoke on Extracellular signal regulated kinase (ERK)cell signaling pathway in her experimental model, which is rat cardiac stem cells."
Microbiology Lab Facility
Microbiology laboratory is being established for sterilization of formulations and biopharmaceuticals as well as testing sterility of nanoemulsions and protein solutions. In addition the Microbiology laboratory will be used for recombinant DNA technology and culturing of bacteria, fungi, yeast and non pathogenic or attenuated viruses. The certified biosafety level 2 laminar hood is already in place and will complement the autoclave, incubator, microscope and cell imaging facility in forming the starting point to build the facility into a full fledged GLP compliant Microbiology laboratory. Antiviral and antibacterial compounds synthesized or isolated by a number of faculty against multiple infections like HIV, Influenza, TB will be tested using the attenuated poxviruses and nonopathogenic mycobacteria.